Physiostigmine - перевод на Английский
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Physiostigmine - перевод на Английский

CHEMICAL COMPOUND
Eserine; Physostigmine hydrochloride; Physiostigmine; C15H21N3O2; Physotigmine; ATCvet code QA03FA90; ATC code S01EB05; ATCvet code QS01EB05; ATC code V03AB19; ATCvet code QV03AB19; Antilirium; Esromiotin; Ezerin; Fysostigmin; Physostol; Physiostigmin; ATCvet code QA03AX90
  • First total synthesis of physostigmine <br>Julian & Pikl (1935)
  • Physostigmine proposed biosynthesis

Physiostigmine      
n. physostigmine, drug used to treat glaucoma
physostigmine      
n. Physiostigmine (Glaukomabehandelndes Medikament)

Определение

physostigmine
[?f??s??'st?gmi:n]
¦ noun Chemistry a compound which is the active ingredient of the Calabar bean and is used medicinally in eye drops.
Origin
C19: from the mod. L. genus name Physostigma + -ine4.

Википедия

Physostigmine

Physostigmine (also known as eserine from éséré, the West African name for the Calabar bean) is a highly toxic parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean and the fruit of the Manchineel tree.

The chemical was synthesized for the first time in 1935 by Percy Lavon Julian and Josef Pikl. It is available in the U.S. under the trade names Antilirium and Isopto Eserine, and as eserine salicylate and eserine sulfate. Today, physostigmine is most commonly used for its medicinal value. However, before its discovery by Sir Robert Christison in 1846, it was much more prevalent as an ordeal poison. The positive medical applications of the drug were first suggested in the gold medal-winning final thesis of Thomas Richard Fraser at the University of Edinburgh in 1862.